Death is the end, unless you’re really, really important
Even though we never got to play the original on PS3, keeping our team of space-saviours alive through two games was tricky enough to cause a space-aneurysm in our space-brains. Almost every important character in the arching story leading to Mass Effect 3 can die based on your decisions, meaning once you lose Garrus on a mission in Mass Effect 2, the big lug won’t be around to help out in the sequel – no do-overs. The notable exception to this rule is Shepard himself, who can be exploded out of a burning space ship, fall through the atmosphere of a planet and crash to the ground, only to be patched up and running around good as new (albeit a couple of years later). The message here is clear: if you’re not saving the universe, the universe ain’t saving you.